Vince Magbuhos was born in Rome, Utaly to Filipino parents who supported him and his brother Wilfrey Jr. to play different sports including football and volleyball. Their father also encouraged them to play basketball, as it could lead to scholarships in the Philippines.
In 2015, the two brothers went home to the Philippines and tried for the University of the East (UE). The trio played for UE in the pre-season but didn't make UE's final lineup.